There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Isosorbide mononitrate is very similar to isosorbide dinitrate. Isosorbide mononitrate (Monoket) can cause some serious health issues. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Natural remedies for depression: Are they effective? This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. 1998 Oct;61(10):577-83. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Organic Nitrate - an overview | ScienceDirect Topics If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Natural Medicines. This content does not have an English version. Egton Medical Information Systems Limited. Isosorbide mononitrate Interactions - Drugs.com If headaches continue or become severe, tell your doctor promptly. This site needs JavaScript to work properly. It is best not to drink alcohol while you are on isosorbide mononitrate. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). https://naturalmedicines.therapeuticresearch.com. If this worries you, talk to your doctor or pharmacist about other options. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. My cardiologist recommended I get on metropolol. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Isosorbide mononitrate - UpToDate Nitroglycerin has an average rating of These headaches may be a sign that the medication is working as it should. So get a ct scan brain apart from cardiology workup. May also be prescribed off label for Esophageal Spasm. Natural Medicines. eCollection 2021. If you miss a dose, take it as soon as you remember. Who should not take Isosorbide Mononitrate? 2005 - 2023 WebMD LLC. Consult your doctor for more details. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. This medicine is available only with your doctor's . Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. No, that's not true all the time. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Click here for an email preview. Take this medication by mouth as directed by your doctor, usually twice a day. https://www.uptodate.com/contents/search. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Dehydration in Buspar, how severe and when it was recovered? Tolerance is more likely to happen if you don't take your dose at the same time every day. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. 2017; doi:10.1016/j.jacc.2016.11.078. You may report side effects to the FDA at 1-800-FDA-1088. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Herbal medications in cardiovascular medicine. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. In Canada - Call your doctor for medical advice about side effects. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Am J Ther. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Accessed Sept. 7, 2022. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. Saper RB. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Accessed Sept. 7, 2022. This is so your doctor can check on your progress. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Limit alcoholic beverages. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Duplication for commercial use must be authorized by ASHP. information is beneficial, we may combine your email and website usage information with Advertising revenue supports our not-for-profit mission. Natural Medicines. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. https://naturalmedicines.therapeuticresearch.com. Limited data from animal studies indicate no adverse effects on the pregnancy or the unborn child. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. If you suffer headaches when taking Isosorbide mononitrate, be patient. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Real test is coronary angiography. It is used to treat and prevent a wide range of different conditions. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Isosorbide Mononitrate - Uses, Side Effects, Substitutes, Composition Zhonghua Yi Xue Za Zhi (Taipei). Isosorbide dinitrate dose 30-120 mg daily in divided doses. . Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. To provide you with the most relevant and helpful information, and understand which Do not flush medications down the toilet or pour them into a drain unless instructed to do so. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Imdur vs. Isordil - RxList Some of these interactions can be life-threatening. Natural Medicines. Accessed Sept. 7, 2022. Isosorbide mononitrate helps to prevent angina chest pain from developing. This site complies with the HONcode standard for trustworthy health information: verify here. Compare a few possible alternatives below. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. This branded product is no longer on the market. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Many common herbal supplements interact with common heart medicines. Do infrared saunas have any health benefits? When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Seek alternatives to the CYP3A4 substrate when possible. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. What special precautions should I follow? Of the total drug interactions, This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Some conditions may become worse when the drug is suddenly stopped. All rights reserved. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Isosorbide mononitrate - Wikipedia The IR version can help treat and prevent angina. St. John's wort. Natural Medicines. Isosorbide Mononitrate - Medicine.com Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. The information on this page is written and peer reviewed by qualified clinicians. Garlic. 2023 eHealthMe.com. These side effects may go away during treatment as your body adjusts to the medicine. Prescription and OTC Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Can isosorbide mononitrate cause problems? Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Store at room temperature away from light and moisture. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. In: Textbook of Natural Medicine. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. It is unknown if this medication passes into breast milk. Try our Symptom Checker Got any other symptoms? If you become pregnant while taking isosorbide, call your doctor. A randomized, double-blind, cross-over study. Valerian: A safe and effective herbal sleep aid? The extended-release tablet usually is taken once daily in the morning. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Ginkgo. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. https://naturalmedicines.therapeuticresearch.com. You may opt-out of email communications at any time by clicking on Danshen. If you have an underactive thyroid gland. Herbal supplements and heart medicines may not mix - Mayo Clinic This product is available in the following dosage forms: There is a problem with Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. If you have any questions about this medicine ask your pharmacist. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Does Isosorbide Mononitrate interact with other drugs you are taking? Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. National Library of Medicine The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Accessed Sept. 7, 2022. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. MBBS, MS - General Surgery, mch neuro surgery. Consult your pharmacist or local waste disposal company. (2) One in 3 patients never experienced headache from the given dosages. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. On the other hand, the ER version can only help prevent angina. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. FOIA Take care, thanks. 88 ratings on Drugs.com. Isosorbide mononitrate systemic 60 mg (A ID). Do not stop taking isosorbide without talking to your doctor. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Generic alternatives may be available. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Let your provider know if they are excessive. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. It can cause your blood pressure to become dangerously low. Things to remember when you fill your prescription. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. We study millions of patients and 5,000 more each day. Browse all drugs on eHealthMe. the unsubscribe link in the e-mail. 55 ratings on Drugs.com. privacy practices. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Eur Heart J. There are 195 drugs known to interact with [2] It is taken by mouth. If you forget to take a dose, take it as soon as you remember. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). Always consult your healthcare provider. Keep all medicines out of the reach and sight of children. It is important that you follow the instructions your doctor gives to you about when to take your doses. Do not change the dosing times unless directed by your doctor. Bookshelf Available for Android and iOS devices. Accessed Sept. 7, 2022. It works to relax your blood vessels. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Accessed Sept. 7, 2022. You need to take it every day in order for it to work. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Daily headaches are a common side effect. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Copyright 2023 IBM Watson Health. You can consult me online for homeopathic treatment. Does Alcohol Raise Your Blood Pressure? What are the side effects of Isosorbide Mononitrate ? It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Upgrade to Patient Pro Medical Professional? Drug interactions may change how your medications work or increase your risk for serious side effects. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Each day, take the first dose when you wake up, then take the second dose 7 hours later. This site complies with the HONcode standard for trustworthy health information: verify here. Isosorbide mononitrate dose and side-effects info | Patient Do not take a double dose to make up for a missed one. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. https://naturalmedicines.therapeuticresearch.com. Unauthorized use of these marks is strictly prohibited. Store in a cool, dry place, away from direct heat and light. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Integrative medicine (complementary and alternative medicine). Otherwise, call a poison control center right away. In: Current Medical Diagnosis & Treatment 2022. This should pass after a few days. The table below contains some of the most common ones associated with isosorbide mononitrate.